Endocrine Abstracts

De novo lipogenesis (DNL) is recognised as potentially contributory to pathogenesis of non-alcoholic fatty liver disease (NAFLD), and could be a factor in the progression of simple steatosis to steatohepatitis, although it contributes a relatively minor amount of whole body fat compared to dietary lipid. Consequently understanding the lipidome during induced DNL may provide insight into potential biomarkers of DNL that could be clinically relevant in those at risk of ...